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Jump to: An investigation of parent-child interactions in anxious adolescents and a pilot evaluation of a novel family treatment | Defining the role of Death Associated Protein Kinase 1 in cell fate using genomic and proteomic analysis | Dissecting the molecular basis of LRRK2 Parkinson's Disease | Dissecting the role of LRRK2 in the regulation of autophagy | Enhancement of Learning and Memory by Flavonoids | High resolution systems biology to determine the role of gut microbiota on type 2 diabetes | Improving interventions for anxious youth: developing understanding and treatment of parents' cognition's and behaviours | MICA: Reducing cardiovascular disease risk through sustainable replacement of saturated fatty acids in milk and dairy products | Neural underpinnings of emotional responding and regulation: antecedents and correlates | Reducing saturated fatty acids in the food chain thorugh alteration of milk fat composition DRINC. | Reducing saturated fatty acids in the food chain through alteration of milk fat composition | Reward and empathy in autism - MRC EXTENSION | The Treatment of Child Anxiety Disorders via Guided CBT Self-Help: A Randomised Controlled Trial - MRC EXTENSION | The modulation of catecholamine-thiol adduct-induced neuronal injury by flavonoids and their metabolites | Therapeutic corneal stem cell delivery using a bioadhesive in situ gelling system | Treatment of Child Anxiety Disorder in the Context of Maternal Anxiety: A Randomised Controlled Trial | Typical and atypical ocular accommodation and convergence characteristics and relationships over the life span | Using FMRI and TMS to probe the functional connectivity of prefrontal cortex and amygdala in top-down regulation of emotion

Number of items: 39.

An investigation of parent-child interactions in anxious adolescents and a pilot evaluation of a novel family treatment

Waite, P. ORCID: https://orcid.org/0000-0002-1967-8028, Parkinson, M., Willetts, L. and Creswell, C. (2014) Modifying the family environment. In: Sburlati, E.S., Lyneham, H.J., Schniering, C.A. and Rapee, R.M. (eds.) Evidence-based CBT for anxiety and depression in children and adolescents: a competencies based approach. John Wiley & Sons, Chichester, pp. 275-300. ISBN 9781118469255

Defining the role of Death Associated Protein Kinase 1 in cell fate using genomic and proteomic analysis

Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: 10.1002/pmic.201700444

Dissecting the molecular basis of LRRK2 Parkinson's Disease

Kara, E., Tucci, A., Manzoni, C., Lynch, D. S., Elpidorou, M., Bettencourt, C., Chelban, V., Manole, A., Hamed, S., Haridy, N., Federoff, M., Preza, E., Hughes, D., Pittman, A., Jaunmuktane, Z., Brandner, S., Xiromerisiou, G., Wiethoff, S., Schottlaender, L., Proukakis, C., Morris, H., Warner, T., Bhatia, K., Korlipara, P., Singleton, A., Hardy, J., Wood, N., Lewis, P. and Houlden, H. (2016) Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain : A Journal of Neurology, 139 (7). pp. 1904-1918. ISSN 1460-2156 doi: 10.1093/brain/aww111

Kiely, A., Ling, H., Asi, Y., Kara, E., Proukakis, C., Schapira, A., Morris, H., Roberts, H., Lubbe, S., Limousin, P., Lewis, P., Lees, A., Quinn, N., Hardy, J., Love, S., Revesz, T., Houlden, H. and Holton, J. (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. Molecular Neurodegeneration, 10 (1). 41. ISSN 1750-1326 doi: 10.1186/s13024-015-0038-3

Manzoni, C., Denny, P., Lovering, R. C. and Lewis, P. A. (2015) Computational analysis of the LRRK2 interactome. PeerJ, 3. 778. ISSN 2167-8359 doi: 10.7717/peerj.778

Manzoni, C., Mamais, A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Abeti, R., Giunti, P., Hardy, J., Cookson, M. R., Tooze, S. A. and Lewis, P. A. (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports, 38 (2). BSR20171669. ISSN 0144-8463 doi: 10.1042/BSR20171669

Ferrari, R., Lovering, R. C., Hardy, J., Lewis, P. A. and Manzoni, C. (2017) Weighted protein interaction network analysis of frontotemporal dementia. Journal of Proteome Research, 16 (2). pp. 999-1013. ISSN 1535-3907 doi: 10.1021/acs.jproteome.6b00934

Manzoni, C., Mamais, A., Roosen, D. A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Hardy, J., Tooze, S. A., Cookson, M. R. and Lewis, P. A. (2016) mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports, 6. 35106. ISSN 2045-2322 doi: 10.1038/srep35106

Dissecting the role of LRRK2 in the regulation of autophagy

Manzoni, C., Denny, P., Lovering, R. C. and Lewis, P. A. (2015) Computational analysis of the LRRK2 interactome. PeerJ, 3. 778. ISSN 2167-8359 doi: 10.7717/peerj.778

Ebanks, K., Lewis, P. A. and Bandopadhyay, R. (2020) Vesicular dysfunction and the pathogenesis of Parkinson's disease: clues from genetic studies. Frontiers in Neuroscience, 13. 1381. ISSN 1662-453X doi: 10.3389/fnins.2019.01381

Civiero, L., Dihanich, S., Lewis, P. A. and Greggio, E. (2014) Genetic, structural, and molecular insights into the function of ras of complex proteins domains. Chemistry and Biology, 21 (7). pp. 809-818. ISSN 1074-5521 doi: 10.1016/j.chembiol.2014.05.010

Enhancement of Learning and Memory by Flavonoids

Vauzour, D., Pinto, J. T., Cooper, A. J. L. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2014) The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling. Biochemical Journal, 463 (1). pp. 41-52. ISSN 0264-6021 doi: 10.1042/BJ20131519

High resolution systems biology to determine the role of gut microbiota on type 2 diabetes

Mora Ortiz, M. and Claus, S. P. (2017) Choline theft-an inside job. Cell Metabolism, 22 (3). pp. 253-255. ISSN 1550-4131 doi: 10.1016/j.chom.2017.08.017

Improving interventions for anxious youth: developing understanding and treatment of parents' cognition's and behaviours

Halldorsson, B., Draisey, J., Cooper, P. and Creswell, C. (2018) Symptoms of social anxiety, depression and stress in parents of children with social anxiety disorder. British Journal of Clinical Psychology, 57 (2). pp. 148-162. ISSN 0144-6657 doi: 10.1111/bjc.12170

Halls, G., Cooper, P. J. and Creswell, C. (2015) Social communication deficits: specific associations with Social Anxiety Disorder. Journal of Affective Disorders, 172. pp. 38-42. ISSN 0165-0327 doi: 10.1016/j.jad.2014.09.040

Alkozei, A., Creswell, C., Cooper, P. and Allen, J. (2015) Autonomic arousal in childhood anxiety disorders: associations with state anxiety and social anxiety disorder. Journal of Affective Disorders, 175. pp. 25-33. ISSN 0165-0327 doi: 10.1016/j.jad.2014.11.056

MICA: Reducing cardiovascular disease risk through sustainable replacement of saturated fatty acids in milk and dairy products

Markey, O., Vasilopoulou, D., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2022) Effect of fat reformulated dairy food consumption on postprandial flow-mediated dilatation and cardiometabolic risk biomarkers compared with conventional dairy: a randomized, controlled trial. American Journal of Clinical Nutrition, 115 (3). pp. 679-693. ISSN 0002-9165 doi: 10.1093/ajcn/nqab428

Hobbs, D. A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Givens, I. D. ORCID: https://orcid.org/0000-0002-6754-6935 (2015) Dairy products: their role in the diet and effects on cardiovascular disease. In: Watson, R. R. and De Meester, F. (eds.) Handbook of Lipids in Human Function: Fatty Acids. AOCS Press, Oxford, pp. 111-130. ISBN 9781630670368

Givens, I. ORCID: https://orcid.org/0000-0002-6754-6935 (2015) Manipulation of lipids in animal-derived foods: can it contribute to public health nutrition? European Journal of Lipid Science and Technology, 117 (9). pp. 1306-1316. ISSN 1438-9312 doi: 10.1002/ejlt.201400427

Neural underpinnings of emotional responding and regulation: antecedents and correlates

Barry, T. J., Murray, L., Fearon, P., Moutsiana, C., Johnstone, T. and Halligan, S. (2017) Amygdala volume and hypothalamic-pituitary-adrenal axis reactivity to social stress. Psychoneuroendocrinology, 85. pp. 96-99. ISSN 1873-3360 doi: 10.1016/j.psyneuen.2017.07.487

Barry, T. J., Murray, L., Fearon, R. M. P., Moutsiana, C., Cooper, P., Goodyer, I. M., Herbert, J. and Halligan, S. L. (2015) Maternal postnatal depression predicts altered offspring biological stress reactivity in adulthood. Psychoneuroendocrinology, 52. pp. 251-60. ISSN 1873-3360 doi: 10.1016/j.psyneuen.2014.12.003

Macdonald, B., Murray, L., Moutsiana, C., Fearon, P., Cooper, P. J., Halligan, S. L. and Johnstone, T. (2016) Altered engagement of autobiographical memory networks in adult offspring of postnatally depressed mothers. Biological Psychology, 118. pp. 147-153. ISSN 0301-0511 doi: 10.1016/j.biopsycho.2016.05.006

Reducing saturated fatty acids in the food chain thorugh alteration of milk fat composition DRINC.

Reducing saturated fatty acids in the food chain through alteration of milk fat composition

Reward and empathy in autism - MRC EXTENSION

Thompson, N. M., Uusberg, A., Gross, J. J. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2019) Empathy and emotion regulation: an integrative account. In: Emotion and Cognition. Progress in Brain Research, 247. Elsevier, pp. 273-304. doi: 10.1016/bs.pbr.2019.03.024

Winkielman, P., Carr, E. W., Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895, Hofree, G. and Kavanagh, L. C. (2016) Mimicry, emotion, and social context: insights from typical and atypical humans, robots, and androids. In: Hess, U. and Fischer, A. (eds.) Emotional Mimicry in Social Context. Studies in Emotion and Social Interaction. Cambridge University Press, Cambridge, UK, pp. 162-191. ISBN 9781107064478

The Treatment of Child Anxiety Disorders via Guided CBT Self-Help: A Randomised Controlled Trial - MRC EXTENSION

Thirlwall, K., Cooper, P. and Creswell, C. (2017) Guided parent delivered cognitive behavioural therapy for childhood anxiety: predictors of treatment response. Journal of Anxiety Disorders, 45. pp. 43-48. ISSN 0887-6185 doi: 10.1016/j.janxdis.2016.11.003

The modulation of catecholamine-thiol adduct-induced neuronal injury by flavonoids and their metabolites

Therapeutic corneal stem cell delivery using a bioadhesive in situ gelling system

The University of Newcastle Upon Tyne , Newcastle upon Tyne ( GB (2020) Transport of cells in hydrogels. US 10,655,120 B2. doi: US 10,655,120 B2

Treatment of Child Anxiety Disorder in the Context of Maternal Anxiety: A Randomised Controlled Trial

Halldorsson, B., Castelijn, S. and Creswell, C. (2019) Are children with social anxiety disorder more likely than children with other anxiety disorders to anticipate poor social performance and reflect negatively on their performance? Journal of Affective Disorders, 245. pp. 561-568. ISSN 0165-0327 doi: 10.1016/j.jad.2018.11.021

Typical and atypical ocular accommodation and convergence characteristics and relationships over the life span

Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686 and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2013) The clinical near gradient stimulus AC/A ratio correlates better with the response CA/C ratio than with the response AC/A ratio. Strabismus, 21 (2). pp. 140-144. ISSN 0927-3972 doi: 10.3109/09273972.2013.786741

Using FMRI and TMS to probe the functional connectivity of prefrontal cortex and amygdala in top-down regulation of emotion

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