Items where Author is "Whalley, Professor Ben"

Article

Jammal, L., Whalley, B. and Barkai, E. (2018) Learning-induced modulation of the effect of neuroglial transmission onsynaptic plasticity. Journal of Neurophysiology, 119 (6). pp. 2373-2379. ISSN 0022-3077 doi: 10.1152/jn.00101.2018

Scheldeman, C., Mills, J. D., Siekierska, A., Serra, I., Copmans, D., Iyer, A. M., Whalley, B. J., Maes, J., Jansen, A. C., Lagae, L., Aronica, E. and de Witte, P. A. M. (2017) mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis. Neurobiology of disease, 108. pp. 225-237. ISSN 1095-953X doi: 10.1016/j.nbd.2017.09.004

Ugbode, C. I., Smith, I., Whalley, B. J., Hirst, W. D. and Rattray, M. (2017) Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. Journal of Neurochemistry, 142 (3). pp. 429-443. ISSN 1471-4159 doi: 10.1111/jnc.14064

Rosenberg, E. C., Patra, P. H. and Whalley, B. J. (2017) Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection. Epilepsy & Behaviour, 70 (Part B). pp. 319-327. ISSN 1525-5050 doi: 10.1016/j.yebeh.2016.11.006

Smith, I., Silveirinha, V., Stein, J. L., de la Torre-Ubieta, L., Farrimond, J. A., Williamson, E. M. and Whalley, B. J. (2017) Human neural stem cell-derived cultures in three- dimensional substrates form spontaneously functional neuronal networks. Journal of Tissue Engineering and Regenerative Medicine, 11 (4). pp. 1022-1033. ISSN 1932-7005 doi: 10.1002/term.2001

Abbassian, H., Whalley, B. J., Sheibani, V. and Shabani, M. (2016) Cannabinoid type 1 receptor antagonism ameliorates harmaline-induced essential tremor in rat. British Journal of Pharmacology, 173 (22). pp. 3196-3207. ISSN 1476-5381 doi: 10.1111/bph.13581

de Carvalho, C., Hoeller, A., Franco, P., Martini, A., Soares, F., Lin, K., Prediger, R., Whalley, B. and Walz, R. (2016) The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole-induced seizure severity in Wistar rats. Epilepsy Research, 127. pp. 160-167. ISSN 0920-1211 doi: 10.1016/j.eplepsyres.2016.08.011

Abbassian, H., Esmaeili, P., Tahamtan, M., Aghaei, I., Vaziri, Z., Sheibani, V., Whalley, B. J. and Shabani, M. (2016) Cannabinoid receptor agonism suppresses tremor, cognition disturbances and anxiety-like behaviors in a rat model of essential tremor. Physiology & Behavior, 164 (Part A). pp. 314-320. ISSN 0031-9384 doi: 10.1016/j.physbeh.2016.06.013

Jammal, L., Whalley, B., Ghosh, S., Lamrecht, R. and Barkai, E. (2016) Physiological expression of olfactory discrimination rule learning balances whole-population modulation and circuit stability in the piriform cortex network. Physiological Reports, 4 (14). e12830. ISSN 2051-817X doi: 10.14814/phy2.12830

Paudyal, A., Dewan, S., Ikie, C., Whalley, B. J., de Tombe, P. P. and Boateng, S. Y. (2016) Nuclear accumulation of myocyte muscle LIM protein is regulated by heme oxygenase 1 and correlates with cardiac function in the transition to failure. Journal of Physiology, 594 (12). pp. 3287-3305. ISSN 1469-7793 doi: 10.1113/JP271809

Smith, I., Haag, M., Ugbode, C., Tams, D., Rattray, M., Przyborski, S., Bithell, A. and Whalley, B. J. (2015) Neuronal-glial populations form functional networks in a biocompatible 3D scaffold. Neuroscience Letters, 609. pp. 198-202. ISSN 0304-3940 doi: 10.1016/j.neulet.2015.10.044

Ibeas Bih, C., Chen, T., Nunn, A. V. W., Bazelot, M., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Whalley, B. J. (2015) Molecular targets of cannabidiol in neurological disorders. Neurotherapeutics, 12 (4). pp. 699-730. ISSN 1933-7213 doi: 10.1007/s13311-015-0377-3

Rosenberg, E. C., Tsien, R. W., Whalley, B. J. and Devinsky, O. (2015) Cannabinoids and epilepsy. Neurotherapeutics, 12 (4). pp. 747-768. ISSN 1933-7213 doi: 10.1007/s13311-015-0375-5

Vogl, C., Tanifuji, S., Danis, B., Daniels, V., Foerch, P., Wolff, C., Whalley, B. J., Mochida, S. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2015) Synaptic vesicle glycoprotein 2A modulates vesicular release and calcium channel function at peripheral sympathetic synapses. The European Journal of Neuroscience, 41 (4). pp. 398-409. ISSN 0953-816X doi: 10.1111/ejn.12799

Hill, A., Jones, N., Smith, I., Hill, C., Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X, Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 and Whalley, B. (2014) Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se. Neuroscience Letters, 566. pp. 269-274. ISSN 0304-3940 doi: 10.1016/j.neulet.2014.03.013

Smith, I., Williamson, E. M., Putnam, S., Farrimond, J. and Whalley, B. J. (2014) Effects and mechanisms of ginseng and ginsenosides on cognition. Nutrition Reviews, 72 (5). pp. 319-333. ISSN 1753-4887 doi: 10.1111/nure.12099

Hill, T., Cascio, M., Romano, B., Duncan, M., Pertwee, R., Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X, Whalley, B. and Hill, A. (2013) Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB 1 receptor-independent mechanism. British Journal of Pharmacology, 170 (3). pp. 679-692. ISSN 1476-5381 doi: 10.1111/bph.12321

Hoppe, J. B., Haag, M., Whalley, B. J., Salbego, C. G. and Cimarosti, H. (2013) Curcumin protects organotypic hippocampal slice cultures 4 from Ab1–42 -induced synaptic toxicity. Toxicology in Vitro, 27 (8). pp. 2325-2330. ISSN 1879-3177 doi: 10.1016/j.tiv.2013.10.002

Jones, N. A., Glyn, S. E., Akiyama, S., Hill, T. D. M., Hill, A. J., Weston, S. E., Burnett, M. D. A., Yamasaki, Y., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Whalley, B. J. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2012) Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Seizure, 21 (5). pp. 344-352. ISSN 1059-1311 doi: 10.1016/j.seizure.2012.03.001

Farrimond, J. A., Whalley, B. and Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X (2012) Non-D9-tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. Behavioural Pharmacology, 23 (1). pp. 113-117. ISSN 0955-8810 doi: 10.1097/FBP.0b013e32834ed832

Vogl, C., Mochida, S., Wolff, C., Whalley, B. and Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 (2012) The SV2A ligand levetiracetam inhibits presynaptic Ca2+ channels via an intracellular pathway. Molecular Pharmacology, 82 (2). pp. 199-208. ISSN 1521-0111 doi: 10.1124/mol.111.076687

Spencer, M. C., Downes, J. H., Xydas, D., Hammond, M. W., Becerra, V. M., Warwick, K., Whalley, B. J. and Nasuto, S. J. ORCID: https://orcid.org/0000-0001-9414-9049 (2011) Multiscale evolving complex network model of functional connectivity in neuronal cultures. IEEE Transactions on Biomedical Engineering, 59 (1). pp. 30-34. ISSN 0018-9294 doi: 10.1109/TBME.2011.2171340

Wang, X., Horswill, J. G., Whalley, B. J. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2011) Effects of the Allosteric Antagonist 1-(4-Chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 Receptor Modulation in the Cerebellum. Molecular Pharmacology, 79 (4). pp. 758-767. ISSN 1521-0111 doi: 10.1124/mol.110.068197

Farrimond, J., Whalley, B. J. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2010) A low delta-9-tetrahydrocannabinol cannabis extract induces hyperphagia in rats. Behavioural Pharmacology, 21 (8). pp. 769-772. ISSN 0955-8810 doi: 10.1097/FBP.0b013e328340a062

Hill, A. J., Weston, S. E., Jones, N., Smith, I., Bevan, S., Williamson, E. M., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Whalley, B. J. (2010) Δ9-tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rat. Epilepsia, 51 (8). pp. 1522-1532. ISSN 0013-9580 doi: 10.1111/j.1528-1167.2010.02523.x

Farrimond, J., Whalley, B. J. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2010) Cannabis constituents modulate ∆9-tetrahydrocannabinol-induced hyperphagia in rats. Psychopharmacology, 210 (1). pp. 97-106. ISSN 0033-3158 doi: 10.1007/s00213-010-1821-z

Aitchison, E., Weston, S. E., Constanti, A. and Whalley, B. J. (2010) Anticholinesterase-induced epileptiform activity in immature rat piriform cortex slices, in vitro. Neuroscience Letters, 473 (3). pp. 252-256. ISSN 0304-3940 doi: 10.1016/j.neulet.2010.02.060

Jones, N. A., Hill, A. J., Smith, I., Bevan, S. A., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Whalley, B. J. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2010) Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. Journal of Pharmacology and Experimental Therapeutics, 332 (2). pp. 569-577. ISSN 0022-3565 doi: 10.1124/jpet.109.159145

Hill, A. J., Jones, N., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Whalley, B. J. (2010) Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. Journal of Neuroscience Methods, 185 (2). 246 -256. ISSN 0165-0270 doi: 10.1016/j.jneumeth.2009.10.007

Whalley, B. J., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Constanti, A. (2009) Investigation of the effects of the novel anticonvulsant compound carisbamate(RWJ-333369) on rat piriform cortical neurones in vitro. British Journal of Pharmacology, 156 (6). pp. 994-1008. ISSN 0007-1188 doi: 10.1111/j.1476-5381.2008.00110.x

Dennis, I., Whalley, B. J. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2008) Effects of Delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes. British Journal of Pharmacology, 154 (6). pp. 1349-58. ISSN 0007-1188 doi: 10.1038/bjp.2008.190

Ma, Y.-L., Weston, S.E., Whalley, B.J. and Stephens, G.J. ORCID: https://orcid.org/0000-0002-8966-4238 (2008) The phytocannabinoid Δ9-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. British Journal of Pharmacology, 154 (1). pp. 204-215. ISSN 0007-1188 doi: 10.1038/bjp.2008.57

Patel, N. A., Weston, S. E., Constanti, A., Halliwell, J. V. and Whalley, B. J. (2007) Cholinergic modulation of intrinsic fibre-evoked excitatory transmission contains a nicotinic component in immature but not adult rat piriform cortex, in vitro. Neuroscience Letters, 425 (1). pp. 43-48. ISSN 0304-3940 doi: 10.1016/j.neulet.2007.08.005

Whalley, B. J. and Constanti, A. (2006) Developmental changes in presynaptic muscarinic modulation of excitatory and inhibitory neurotransmission in rat piriform cortex in vitro: relevance to epileptiform bursting susceptibility. Neuroscience, 140 (3). pp. 939-956. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2006.02.046

Whalley, B. J., Postlethwaite, M. and Constanti, A. (2005) Further characterization of muscarinic agonist-induced epileptiform bursting activity in immature rat piriform cortex, in vitro. Neuroscience, 134 (2). pp. 549-566. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2005.04.018

Whalley, B. J., Wilkinson, J. D., Williamson, E. M. and Constanti, A. (2004) A novel component of cannabis extract potentiates excitatory synaptic transmission in rat olfactory cortex in vitro. Neuroscience Letters, 365 (1). pp. 58-63. ISSN 0304-3940 doi: 10.1016/j.neulet.2004.04.044

Wilkinson, J.D., Whalley, B. J., Baker, D., Pryce, G., Constanti, A., Gibbons, S. and Williamson, E. M. (2003) Medicinal cannabis: is delta9-tetrahydrocannabinol necessary for all its effects? Journal of Pharmacy and Pharmacology, 55 (12). pp. 1687-1694. ISSN 0022-3573 doi: 10.1211/0022357022304

Book or Report Section

Turner, S. E., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Iversen, L. and Whalley, B. J. (2017) Molecular pharmacology of phytocannabinoids. In: Kinghorn, A. D., Falk, H., Gibbons, S. and Kobayashi, J.'i. (eds.) Phytocannabinoids. Progress in the Chemistry of Organic Natural Products, 103. Springer, pp. 61-101. ISBN 9783319455396 doi: 10.1007/978-3-319-45541-9_3

Williams, C. M., Whalley, B. J. and McCabe, C. ORCID: https://orcid.org/0000-0001-8704-3473 (2015) Cannabinoids & appetite (dys)regulation (obesity). In: Fattore, L. (ed.) Cannabinoids in Neurologic and Mental Disease. Academic Press, pp. 315-342. ISBN 9780124170414

Warwick, K., Nasuto, S. J. ORCID: https://orcid.org/0000-0001-9414-9049, Becerra, V. M. and Whalley, B. J. (2011) Experiments with an in-vitro robot brain. In: Yang, C. (ed.) Computing with instinct: rediscovering artificial intelligence. Lecture notes in computer science (5987). Springer, pp. 1-16, 1st Edition, XIII, 163 p. ISBN 9783642197567 (Sub series: lecture notes in artifical intelligence)

Weston, S. E., Whalley, B.J., Wilkinson, J.D. and Williamson, E.M. (2007) Medicinal cannabis: new findings on extracts and minor cannabinoids. In: Capasso, A. (ed.) Recent developments in medicinal plant research. Research Signpost, Trivandrum, Kerala, India, pp. 39-62. ISBN 9788130801605

Conference or Workshop Item

Miranda, E. R., Nasuto, S. ORCID: https://orcid.org/0000-0001-9414-9049, Troisi, A. R., Downes, J., Chiaramonte, A., Spencer, M., Hammond, M., Xydas, D., Whalley, B., Becerra, V. and Warwick, K. (2011) A musical instrument using in vitro neural networks. In: International Computer Music Conference (ICMC 2011), 31 Jul - 5 Aug 2011, Huddersfield, pp. 567-570.

Valderrama-Gonzalez, G. D., Gasson, M. N., Warwick, K. and Whalley, B. J. (2010) Prosthesis grasp reflex via peripheral nerve control: an in vitro study. In: IEEE 2010 9th International Conference on Cybernetic Intelligent Systems (CIS), 1-2 September 2010, University of Reading, UK, pp. 20-25. (IEEE, London)

Xydas, D., Spencer, M., Downes, J., Hammond, M. W. J., Becerra, V. M., Warwick, K., Whalley, B. J. and Nasuto, S. J. ORCID: https://orcid.org/0000-0001-9414-9049 (2010) Application of Poisson-based hidden Markov models to in-vitro neuronal data. In: 9th IEEE International Conference on Cybernetic Intelligent Systems, 1-2 Sept 2010, Reading, UK.

Spencer, M., Xydas, D., Downes, J. H., Hammond, M., Becerra, V., Warwick, K., Whalley, B. J. and Nasuto, S. J. ORCID: https://orcid.org/0000-0001-9414-9049 (2010) Investigation of spatio-temporal dependencies in neuronal functional connectivity. In: 9th IEEE International Conference on Cybernetic Intelligent Systems, 1-2 Sept 2010, Reading, UK.

Weston, S. E., Williamson, E. M., Constanti, A., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Whalley, B. J. (2006) Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity. In: British Pharmacological Society Winter Meeting 2006.

Book

Whalley, B.J., Fletcher, K.E., Weston, S. E., Howard, R.L. and Rawlinson, C.F. (2008) Foundation in pharmacy practice. Pharmaceutical, London. ISBN 9780853697473