A new crystalline form of αβ-D-lactose prepared by oven drying a concentrated aqueous solution of D-lactose

Nicholls, D., Elleman, C., Shankland, N. and Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155 (2019) A new crystalline form of αβ-D-lactose prepared by oven drying a concentrated aqueous solution of D-lactose. Acta Crystallographica Section C - Crystal Structure Communications, 75 (7). pp. 904-909. ISSN 1600-5759 doi: 10.1107/S2053229619008210

Abstract/Summary

A new crystalline form of αβ-D-lactose (C12H22O11, Z' = 2) has been prepared by rapid drying of an approximately 40 % w/v syrup of D-lactose. Initially identified from its novel powder X-ray diffraction pattern, the monoclinic crystal structure was solved from a microcrystal recovered from the generally polycrystalline, mixed-phase residue obtained at the end of the drying step. This is the second crystalline form of αβ-D-lactose to be identified and it has a high degree of structural 3D similarity to the previously identified triclinic form.