The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome ‘at-risk’ population syndrome.

Fava, F., Gitau, R., Griffin, B.A., Tuohy, K. M., Gibson, G. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2013) The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome ‘at-risk’ population syndrome. International Journal of Obesity, 37 (2). pp. 216-223. ISSN 0307-0565 doi: 10.1038/ijo.2012.33

Abstract/Summary

An obese-type human microbiota with an increased Firmicutes:Bacteroidetes ratio has been described that may link the gut microbiome with obesity and metabolic syndrome (MetS) development. Dietary fat and carbohydrate are modifiable risk factors that may impact on MetS by altering the human microbiome composition. We determined the effect of the amount and type of dietary fat and carbohydrate on faecal bacteria and short chain fatty acid (SCFA) concentrations in people ‘at risk’ of MetS.