Items where Author is "Vaiyapuri, Professor Sakthi"

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Carbonell, R. C. C., Garcês-Filho, A. Q., Galan, L. E. B., Romanazzi, M., Malachias-Pires, G. M., Almeida, J. R., Nattrodt, J. J. M., Carbonell, J. d. L. B., Cerni, F. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Pucca, M. B. (2025) Vacuum-assisted wound therapy in Bothrops snakebite injuries: a case series from the Brazilian Amazon. Journal of Clinical Medicine. ISSN 2077-0383 (In Press)

Romanazzi, M., Filardi, E. T. M., Pires, G. M. M., Cerveja, M. F., Melo-dos-Santos, G., Oliveira, I. S., Ferreira, I. G., Cerni, F. A., Santos-Filho, N. A., Monteiro, W. M., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Pucca, M. B. (2025) The versatility of serine proteases from Brazilian Bothrops venom: their roles in snakebites and drug discovery. Biomolecules, 15 (2). 154. ISSN 2218-273X doi: 10.3390/biom15020154

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Falabella, P., eds. (2024) Venom collection. Scientific Reports. Nature Publishing Group. (In Press) (ISSN: 2045-2322)

Sonavane, M., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Rajan, E., Williams, H. F., Townsend, F., Cornish, E., Mitchell, R. D., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Intramuscular bleeding and formation of microthrombi during skeletal muscle damage caused by a snake venom metalloprotease and a cardiotoxin. Toxins, 15 (9). 530. ISSN 2072-6651 doi: 10.3390/toxins15090530

Richards, N. J., Alqallaf, A., Mitchell, R. D., Parnell, A., Haidar, H. B., Almeida, J. R., Williams, J., Vijayakumar, P., Balogun, A., Matsakas, A., Trim, S. A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Indian ornamental tarantula (Poecilotheria regalis) venom affects myoblast function and causes skeletal muscle damage. Cells, 12 (16). 2074. ISSN 2073-4409 doi: 10.3390/cells12162074

Senthilkumaran, S., Patel, K., Rajan, E., Vijayakumar, P., Miller, S. W., Rucavado, A., Gilabadi, S., Sonavane, M., Richards, N. J., Williams, J., Williams, H. F., Trim, S. A., Thirumalaikolundusubramanian, P., Gutiérrez, J. M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Peripheral arterial thrombosis following Russell’s viper bites. TH Open, 07 (02). e168-e183. ISSN 2567-3459 doi: 10.1055/s-0043-1769625

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Kadam, P., Chandrasekharuni, G., Oliveira, I. S., Senthilkumaran, S., Salim, A., Patel, K., Sachett, J. d. A. G. and Pucca, M. B. (2023) Multifaceted community health education programs as powerful tools to mitigate snakebite-induced deaths, disabilities, and socioeconomic burden. Toxicon: X, 17. 100147. ISSN 2590-1710 doi: 10.1016/j.toxcx.2022.100147

Senthilkumaran, S., Miller, S. W., Williams, H. F., Thirumalaikolundusubramanian, P., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2022) Hirata’s disease (insulin autoimmune syndrome) following envenomation by a common krait. Toxicon, 219. 106923. ISSN 0041-0101 doi: 10.1016/j.toxicon.2022.09.009

Senthilkumaran, S., Miller, S. W., Williams, H. F., Savania, R., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Development of Wunderlich Syndrome following a Russell’s viper bite. Toxicon, 215. pp. 11-16. ISSN 0041-0101 doi: 10.1016/j.toxicon.2022.06.004

Alqallaf, A., Engelbeen, S., Palo, A., Cutrupi, F., Tanganyika-de Winter, C., Plomp, J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Aartsma-Rus, A., Patel, K. and Putten, M. v. (2022) The therapeutic potential of soluble activin type IIB receptor treatment in a limb girdle muscular dystrophy type 2D mouse model. Neuromuscular Disorders, 32 (5). pp. 419-435. ISSN 0960-8966 doi: 10.1016/j.nmd.2022.03.002

Arathisenthil, S. V., Senthilkumaran, S., Vijayakumar, P., Savania, R., Williams, H. F., Elangovan, N., Bicknell, A. B., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Rapid development of a salivary calculus in submandibular gland and its potential causes in a young victim following Russell’s viper bite. Toxicon, 206. pp. 85-89. ISSN 0041-0101 doi: 10.1016/j.toxicon.2021.12.018

Senthilkumaran, S., Vijayakumar, P., Savania, R., Vaiyapuri, R., Elangovan, N., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Splenic rupture and subsequent splenectomy in a young healthy victim following Russell’s viper bite. Toxicon, 204. pp. 9-13. ISSN 0041-0101 doi: 10.1016/j.toxicon.2021.10.010

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: 10.1182/blood.2019004575

Patel, K., Simbi, B., Ritvos, O., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Dhoot, G. K. (2019) Dysregulated cell signalling and reduced satellite cell potential in ageing muscle. Experimental Cell Research, 385 (2). 111685. ISSN 0014-4827 doi: 10.1016/j.yexcr.2019.111685

Ravishankar, D., Albadawi, D., Chaggar, V., Patra, P., Williams, H., Salamah, M., Vaiyapuri, R., Dash, P., Patel, K., Watson, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation. European Journal of Pharmacology, 862. 172627. ISSN 0014-2999 doi: 10.1016/j.ejphar.2019.172627

Paolini, A., Omairi, S., Mitchell, R., Vaughan, D., Matsakas, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ricketts, T., Rubinsztein, D. C. and Patel, K. (2018) Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury. Scientific Reports, 8. 9062. ISSN 2045-2322 doi: 10.1038/s41598-018-27429-7

Williams, H. F., Vaiyapuri, R., Gajjeraman, P., Hutchinson, G., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Bicknell, A. B. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: the views of clinicians. Toxicon, 130. pp. 44-46. ISSN 0041-0101 doi: 10.1016/j.toxicon.2017.02.025

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis, Thrombosis, and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1079-5642 doi: 10.1161/ATVBAHA.116.308093

Crescente, M., Pluthero, F. G., Li, L., Lo, R. W., Walsh, T. G., Schenk, M. P., Holbrook, L. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Ali, M. S., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Falet, H., Jones, I. M. ORCID: https://orcid.org/0000-0002-7738-2516, Poole, A. W., Kahr, W. H. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Intracellular trafficking, localization, and mobilization of platelet-borne thiol isomerases. Arteriosclerosis, Thrombosis, and Vascular Biology, 36 (6). pp. 1164-1173. ISSN 1079-5642 doi: 10.1161/ATVBAHA.116.307461

Mazet, F., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Tindall, M. J., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications. Scientific Reports, 5. 16995. ISSN 2045-2322 doi: 10.1038/srep16995

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis, Thrombosis, and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1079-5642 doi: 10.1161/ATVBAHA.115.306130

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sunagar, K., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Jackson, T. N. W., Reeks, T. and Fry, B. G. (2015) Kallikrein enzymes. In: Fry, B. (ed.) Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. Oxford University Press, New York, pp. 267-280. ISBN 9780199309399

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sunagar, K., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Jackson, T. N. W., Reeks, T. and Fry, B. G. (2015) Kallikrein enzymes. In: Fry, B. (ed.) Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery:. Oxford University Press, New York, pp. 267-280. ISBN 9780199309399

Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hussain, U., Tucker, K. L., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2014) Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3. Arteriosclerosis, Thrombosis, and Vascular Biology, 34 (9). pp. 1968-1976. ISSN 1079-5642 doi: 10.1161/ATVBAHA.114.304097

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Vaiyapuri, R., Ashokan, R., Ramasamy, K., Nattamaisundar, K., Jeyaraj, A., Chandran, V., Gajjeraman, P., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2013) Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India. PLOS ONE, 8 (11). e80090. ISSN 1932-6203 doi: 10.1371/journal.pone.0080090

Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Antithrombotic actions of statins involve PECAM-1 signalling. Blood, 122 (18). pp. 3188-3196. ISSN 0006-4971 doi: 10.1182/blood-2013-04-491845

Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Antithrombotic actions of statins involve PECAM-1 signalling. Blood, 122 (18). pp. 3188-3196. ISSN 0006-4971 doi: 10.1182/blood-2013-04-491845

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2013) Sequence and functional analysis of viper venom proteolytic enzymes. Lambert Academic Publishing, Saarbrucken. ISBN 9783659399183

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2013) Sequence and functional analysis of viper venom proteolytic enzymes. Lambert Academic Publishing, Saarbrucken. ISBN 9783659399183

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hutchinson, E. G., Ali, M. S., Dannoura, A., Stanley, R. G., Harrison, R. A., Bicknell, A. B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions. The Journal of Biological Chemistry, 287 (31). pp. 26235-26244. ISSN 1083-351X doi: 10.1074/jbc.M112.381483

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hutchinson, E. G., Ali, M. S., Dannoura, A., Stanley, R. G., Harrison, R. A., Bicknell, A. B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions. The Journal of Biological Chemistry, 287 (31). pp. 26235-26244. ISSN 1083-351X doi: 10.1074/jbc.M112.381483

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation, 125 (20). pp. 2479-2491. ISSN 0009-7322 doi: 10.1161/CIRCULATIONAHA.112.101246

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation, 125 (20). pp. 2479-2491. ISSN 0009-7322 doi: 10.1161/CIRCULATIONAHA.112.101246

Elashry, M. I., Collins-Hooper, H., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2012) Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice. Journal of Anatomy, 220 (6). pp. 603-611. ISSN 0021-8782 doi: 10.1111/j.1469-7580.2012.01503.x

Elashry, M. I., Collins-Hooper, H., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2012) Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice. Journal of Anatomy, 220 (6). pp. 603-611. ISSN 0021-8782 doi: 10.1111/j.1469-7580.2012.01503.x

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, G. (2011) Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. PLoS ONE, 6 (6). e21532. ISSN 1932-6203 doi: 10.1371/journal.pone.0021532

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, G. (2011) Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. PLOS ONE, 6 (6). e21532. ISSN 1932-6203 doi: 10.1371/journal.pone.0021532

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Watson, K. A., Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2010) Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. PLOS Neglected Tropical Diseases, 4 (8). e796. ISSN 1935-2727 doi: 10.1371/journal.pntd.0000796

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Harrison, R. A., Bicknell, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2010) Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros. PLoS ONE, 5 (3). e9687. ISSN 1932-6203 doi: 10.1371/journal.pone.0009687

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Harrison, R. A., Bicknell, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2010) Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros. PLOS ONE, 5 (3). e9687. ISSN 1932-6203 doi: 10.1371/journal.pone.0009687

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2008) Sequence, Structure and Functional Studies of Viper Venom Proteolytic Enzymes. PhD thesis, University of Reading.

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2008) Sequence, Structure and Functional Studies of Viper Venom Proteolytic Enzymes. PhD thesis, University of Reading.

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