Hippocampal adaptations in Mild Cognitive Impairment patients are modulated by bilingual language experiences

Voits, T., Rothman, J., Calabria, M., Robson, H., Aguirre, N., Cattaneo, G., Costumero, V., Hernández, M., Juncadella Puig, M., Marín-Marín, L., Suades, A., Costa, A. and Pliatsikas, C. ORCID: https://orcid.org/0000-0001-7093-1773 (2024) Hippocampal adaptations in Mild Cognitive Impairment patients are modulated by bilingual language experiences. Bilingualism: Language and Cognition, 27 (2). 263 -273. ISSN 1469-1841 doi: 10.1017/S1366728923000354

Abstract/Summary

Bilingualism has been shown to contribute to increased resilience against cognitive aging. One of the key brain structures linked to memory and dementia symptom onset, the hippocampus, has been observed to adapt in response to bilingual experience, at least in healthy individuals. However, in the context of neurodegenerative pathology, it is yet unclear what role previous bilingual experience might have in terms of sustaining integrity of this structure or related behavioral correlates. The present study adds to the limited cohort of research on the effects of bilingualism on neurocognitive outcomes in Mild Cognitive Impairment (MCI) using structural brain data. We investigate whether bilingual language experience (operationalized as language entropy) results in graded neurocognitive adaptations within a cohort of bilinguals diagnosed with MCI. Results reveal a non-linear effect of bilingual language entropy on hippocampal volume, although it does not predict episodic memory performance, nor age of MCI diagnosis.